Circadian rhythms are controlled by evolutionarily conserved internal clocks residing in most tissues of the body. It is responsible for controlling circadian rhythms. It contains several cell types and several different peptides and neurotransmitters. This master pacemaker can synchronize circadian oscillators in peripheral tissues, yet underlying neural and humoral mechanisms remain obscure.
How these time cues act in concert to entrain tissue-specific oscillators and evoke diverse physiological responses is poorly understood. Nevertheless, these processes clearly involve the endocrine system. The rhythmic production and circulation of many hormones and metabolites within the endocrine system is instrumental in regulating regular physiological processes such as reproduction, blood pressure, and metabolism.
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